1/17/2023 0 Comments Prism essential channel listHere, we report that in mouse hair cells, TMC1, but not TMC2, provides a background leak conductance, with properties distinct from those of the MET channels. However, whether TMCs have a non-MET role remains elusive in mammals. ![]() TMCs were also found to regulate biological processes other than MET in invertebrates, ranging from sensations to motor function. Hearing sensation relies on the mechano-electrical transducer (MET) channel of cochlear hair cells, in which transmembrane channel-like 1 (TMC1) and transmembrane channel-like 2 (TMC2) have been proposed to be the pore-forming subunits in mammals.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |